The Chruszcz lab studies the interactions of the human immune system with pathogens and allergens. We are interested in the ways by which pathogens and allergens deregulate or deceive the immune system, and how such processes influence human health. In addition, our research interests include mechanisms of bacterial growth in mammalian host organisms, with a special emphasis on a microorganism’s ability to acquire nutrients from the host. We believe that structural studies are indispensable for the understanding of biological/biochemical processes. Thus, we are using structural biology techniques (especially X-ray crystallography) to obtain experimental models of macromolecules of interest.